DNA Project Background
Background
This Project evolved from the need to identify specific Cooper family members,
the linkage between different Cooper family lines and to dispel current
misinformation. DNA technology was employed for the aforementioned
reasons and create continuity between the many Cooper lineages which have been
identified. To provide for communications the group will eventually maintain an Internet
discussion group and at a website to be designated later.
Despite extensive research, it remains uncertain if or how these lineages
relate to one another. There is also no consensus about the origin of the
Cooper surname. Did this surname derive from a common ancestor or from among
totally unrelated individuals 500-700 years ago?
Like many other genealogists, Cooper family researchers have hit 'brick walls'
when the 'paper trail' leading back into their past has evaporated. Until
recently, the possibility of scaling those brick walls, except for the random
discovery of long lost documents, was remote. A new tool in genealogy,
involving the testing of a person's DNA, emerged and holds the promise of
casting new light on elusive ancestors.
The known lineage descriptions which have already been recorded should help us
interpret and benefit from the Project results. With adequate sampling, the
results of this Project may assist researchers by pointing to those lineages
where relationships are more likely to exist. Such evidence might permit
researchers to focus their collaborative effort in more productive directions.
The Genetics
This discussion of the genetics of DNA testing has been deliberately
simplified. The hazard of doing so is to misrepresent the facts. We
apologize in advance for any such misrepresentations. Anyone interested in a
more technical and scientifically correct explanation is encouraged to follow
the links provided elsewhere on this website.
Although genetic research is not new, its use in genealogy is relatively
recent. This application has been given the name "genetic genealogy." It is
the branch of knowledge arising out of the study of genes first identified in
1909 for identification of inherited physical characteristics. Later, it was
found that deoxyribonucleic acid (DNA) was contained in chromosomes and acted
as a carrier of genetic information. Since 1940, the chemical nature of DNA
has become a science revealing more and more of the mysteries that make up the
human body. It now has become a science that permits the identification of
individuals by the use of DNA.
DNA is used widely in criminal investigations, court proceedings in paternity
cases, and other issues requiring individual identification. Talk shows and
other media have popularized identifying fathers of children using DNA.
Professor Bryan Sykes of Oxford University in England made headlines several
years ago when he reported on the results of his research using mitochondrial
DNA samples. More recently, the analysis of the Y-chromosome has been used in
genealogical research. Y-chromosome testing offers the advantage of being
found only in males. Thus, a father-son relationship following a single
surname can be traced through multiple generations.
At this time, the Cooper DNA Project deals only with Y-chromosome testing.
The reason that only male subjects are used in Y-chromosome testing is the
genetic distinction between females and males. Females have two
X-chromosomes, one of which is inherited from her mother and the other from
her father. Males have one X-chromosome, from his mother, and one
Y-chromosome, from his father. In the laboratory, the two X-chromosomes of
the female cannot be distinguished from one another. However, in the male,
because the Y-chromosome is a different length than the X-chromosome, it can
be distinguished from the X-chromosome. And, since the Y-chromosome is
inherited from the male's father, it is, generally speaking, an identical copy
of the father's Y-chromosome (except for certain changes described below).
The mitochondrial DNA which is also used in certain types of genealogy
research does not come from chromosomes at all. It is derived from parts of
the cell outside the nucleus (where chromosomes are found). Both males and
females have mitochondrial DNA. It is inherited from the child's mother, and
she inherited it from her mother. Thus, this line of research does not follow
a surname's descends. Mitochondrial DNA is more expensive to analyze in the
laboratory. And the results are much more difficult to interpret than those
from Y-chromosome testing.
In a laboratory using special equipment, scientists are able to identify and
'measure' different elements of the Y-chromosome. These elements are called
markers. As of today, over 25 separate markers have been identified for an
individual Y-chromosome sample. Additional research will probably identify
more markers in the future.
For each sample, laboratory analysis can determine a 'value' of each of these
markers. This 'value' is basically a 'measurement' of each marker. For
example, the 'value' of Marker #1 might be 13, for #2 it might be 24, for #3
it might be 15, and so on. (Remember, this explanation is a gross
simplification of a very complex subject.)
Ordinarily, the value of each marker of a father and his biological son is
identical. In the above example, both father and son would test #1=13, #2=24,
#3=15, (and so on through the number of markers tested).
Occasionally, a change occurs in one of these markers between a father and
son. These natural, but infrequent, changes are called mutations. For
example, if one of the markers described above (say, #2) mutated in the son,
then #2 might be 24 in the father and 25 in the son. If that son had a son of
his own, his son's #2 marker would also be 25. The mutation could be down one
number (to 23) as well as up one number.
It isn't known how often these mutations occur. Current scientific estimates
indicate that many generations elapse between significant mutations. These
mutations do not occur in a neat and orderly manner. Recent evidence
indicates that some markers may mutate more frequently that others.
What is important in genealogy is that such mutations do occur. And, it isn't
the number assigned to each marker that is important; it is the comparison of
a set of numbers from one sample with those of other samples.
For example, let's say six participants named Jones produced 4-marker test
results of #1=14, #2= 22, #3=15, #4=10. Since these are identical values, one
might conclude that these six males were closely related. It wouldn't mean
they are father and sons, or that they are brothers, just that they are
closely related.
Now, let's say a seventh participant named Jones produced 4-marker test
results of #1=13, #2=21, #3=13, #4=11. Because these results are so different
from those of the first six participants, one might conclude that this person
is not closely related to the other six (and might not be related at all).
In addition to naturally occurring mutations, there are several other reasons
why one set of numbers might be different from others within a family group.
One of these is adoptions. Historically, it was not uncommon for a male to
adopt the child, or children, of others and raise them as his own. Looking
back several hundred years and considering the hazards of everyday living
(accidents, diseases, wars, etc.), it isn't surprising that many orphans
needed caring for. These may have been the children of a wife's sister, or of
a neighbor. Adoption procedures may have been quite simple; the child or
children just assumed the name of the adopting father and that was that. Of
course, the adopted boys carried the Y-chromosome of their biological fathers,
so there would be little or no similarity to their adopted surname.
Another reason for differences involves illegitimacy. It's a subject that no
one wants to admit might have occurred in their ancestral past, but, although
probably rare, such occurrences did happen.
Finally, there may be instances where a man simply changes his name, for
whatever reason seems important to him. Thus, although he assumes a surname
being tested, his Y-chromosome test will not correlate with those which are a
biological part of that surname group.
If any of these circumstances occurred 12-15 generations ago, the correct
explanation is probably lost to history.
As discussed above, the results of this Project may find a number of
significantly different sets of markers among the various Cooper lineages.
Careful analysis of these differences may suggest that the Cooper surname is
more likely derived from a number of unrelated ancestors rather than a common
ancestor. It may also shed some interesting light on the various spellings
which drives some Cooper researchers slightly crazy (spellings like Cuper,
Couper, Cowper, etc.).
For those who may be concerned about these DNA tests revealing medical
conditions or other personal information, be aware that the Y-chromosome tests
are not made on regions of the cell which are used for medical diagnostic
purposes. Those are tests of a different type for which other regions of the
cell are used.
Also, Y-chromosome testing is not the kind of analysis which might identify
physical characteristics, or prove a paternity, or link a suspect to a crime
scene. Those kinds of DNA analysis are totally different from the
Y-chromosome testing we are using.